Prostate cancer is the most common cancer in men. It varies in how aggressive it is, and many prostate cancers are very slow-growing and do not cause death. Advanced prostate cancer most commonly spreads to the lymph nodes and bones.

Prostate cancer is almost always androgen-dependent, meaning they rely on androgen hormones (e.g., testosterone) to grow.

Epidemiology:

• Prostate cancer is a common condition and up to 30,000 men are diagnosed with the condition each year. Up to 9,000 will die in the UK from the condition per year.

Pathology:

• 95% are caused by adenocarcinomas and are in the peripheral zones of the prostate

Risk factors:

• Age >50 yrs
• Black African or caribbean origin
• Family Hx
• Anabolic steroids

PC

May be asymotomatic or present with LUTS similar to BPH (Hesitancy, frequency, weak flow, terminal dribbling, nocturia)

Other Sx:

• Haematuria
• Erectile dysfunction