Pneumonia describes an inflammatory condition affecting the alveoli of the lungs, in the vast majority of patients is due to a secondary bacterial infection
Aetiology
Community acquired pneumonia (CAP) may be caused by the following infectious agents:
- Streptococcus pneumoniae (accounts for around 80% of cases) - can cause reactivation of HSV resulting in cold sores
- Haemophilus influenzae (common in patients with COPD)
- Staphylococcus aureus: commonly after influenza infection
- Atypical pneumonias:
- Mycoplasma pneumoniae - AHA and erythema multiforme may be seen
- Legionella pneumophillia - commonly secondary to infected AC units
- Klebsiella pneumoniae is classically in alcoholics
- Pneumocystis Jiroveci - Typically in patients with HIV
- Causes of CAP in animal hide importers/sorters - Bacillus anthracis, coxiella burnettii
- Causes of CAP in exposure to birds - chlamydia psitacci (psittacosis), bats/bat dropping exposure, Histoplasma capsulatum (a fungus, classically affects cave-explorers)
- viruses - most commonly influenza A - can predispose staph A
Idiopathic interstitial pneumonia: a group of non-infective causes of pneumonia. Examples include cryptogenic organizing pneumonia which describes a form of bronchiolitis that may develop as a complication of rheumatoid arthritis or amiodarone therapy.
Classification:
- CAP: pneumonia developed outside of the hospital
- HAP: pneumonia occuring 48 hours or more after admission
*Causative organisms and 1st line Abx vary