Nearly all cases of thyroid disease are caused by intrinsic thyroid disease

Hyperthyroidism - over-production of thyroid hormone by the thyroid gland

Thyrotoxicosis - an abnormal and excessive quantity of thyroid hormone in the body.

Primary hyperthyroidism - Thyroid pathology

Secondary hyperthyroidism - Over stimulation, Hypothalamus or pituitary pathology

Causes

Graves disease

Toxic multinodular goitre

• Solitary toxic thyroid nodule - This is where a single abnormal thyroid nodule is acting alone to release thyroid hormone. The nodules are usually benign adenomas. They are treated with surgical removal of the nodule.
• Thyroiditis (e.g. De Quervain’s, acute phase of Hashimoto’s, postpartum and drug-induced thyroiditis)
• Post-partum thyroiditis
• Amiodarone induced thyrotoxicosis
• Immunotherapy induced

PC

• Sweating and heat intolerance
• Weight loss
• Fatigue