Overview

• cause of peripheral neuropathy
• antibody mediated inflammation results in segmental demyelination of peripheral nerves
• males more commonly affected than females
• features similar to Guillain-Barre syndrome (GBS), with motor features predominating. GBS is much more acute in onset.
• more insidious onset, over weeks to months - often thought of as the chronic version of GBS
• high protein content in the CSF
• treatment with steroids and immunosuppressants may have a role (unlike in GBS)