Fusion inhibitors - inhibit the gp41 receptor blocking fusion of virus to target cell membrane - Enfuvirtide
S/E: pancreatitis
Chemokine receptor antagonists (CCR5 antagonists) - Blockade of HIV binding to co- factor for cell entry - Maraviroc
*some people lack CCR5 - these people cant be infected with HIV
S/E: Nausea, diarrhoea
NRTIs - Tenofovir - block the reversal process from RNA into DNA by mimicking the nucleoside and blocking the sequence
S/E: rash, SJS, renal impairment, osteoperosis
NNRTI - (these block the enzyme in other ways without just mimicking the nucleoside) - Efavirenz
Integrase Inhibitors (INIs) - block viral integrase - Dolutegravir
Protease inhibitors - prevent cleavage of polyprotein into different components of the virus - Lopinavir